불소도포 후 시간 경과에 따른 우치 인공우식법랑질의 표면미세경도 변화
The remineralization effect of topical fluoride agents on artificial enamel caries
이민선, 박덕영, 마득상,
소속 상세정보
이민선 ( Lee Min-Sun ) - 강릉원주대학교 치과대학 예방치학교실 및 구강과학연구소
박덕영 ( Park Deok-Young ) - 강릉원주대학교 치과대학 예방치학교실 및 구강과학연구소
마득상 ( Ma Deuk-Sang ) - 강릉원주대학교 치과대학 예방치학교실 및 구강과학연구소
KMID : 0355420120360020085
Abstract
Objectives: The aim of this study was to compare the remineralization effect of the topical fluoride agents on artificial enamel caries, under the chemical pH cycling model, using surface microhardness.
Methods: Bovine enamel specimens, embedded in acrylic resin with the labial surfaces exposed, were
developed artificial enamel caries. Thereafter, this study used 56 samples on VHN 25-45. The experimental groups were divided into 4 groups: control, 2% NaF solution, 1.23% APF gel, 5% NaF varnish. Samples, except in the control group, were applied to each topical fluoride agent for 4 minutes. All groups were exposed to a pH cycling model, which consisted of demineralization (4 hours) and remineralization (20 hours) for 17 days. The Vickers surface microhardness number (VHN) was measured, using the microhardness tester. The results were analyzed, using a repeated measures analysis of variance of a general linear model, and compared the baseline, each day, using a contrast analysis (simple) about
within a subject factor at a significance level of 0.05.
Results: Result of a repeated measures analysis regarding the surface microhardness of topical fluoride agents, there were significant differences at P -values of within and between the subject factor (P<0.001,0.034). VHN of the experiment groups were higher than that of the baseline, until 10 days after a fluoride application, except in the control group (P<0.001). However, there were no significant differences between VHN at the baseline and 14 days after a fluoride application (P>0.05).
Conclusions: In this study, although there were significant differences at P -values of within and between
the subject factor, there were no significant differences between the experiment groups on chemical pH cycling model in vitro, and it was limited to utilize this result in a clinical situation of the fluoride application.
키워드
Artificial enamel caries; Chemical pH cycling; Topical fluoride agents
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